منابع مشابه
Genetic susceptibility of cervical cancer
Epidemiological and laboratory-based studies have identified infection with one of 15 high-risk human papillomavirus (HPV) types as a necessary but not sufficient cause of cervical cancer. The prevalence of genital HPV infections is high in young women, but most of the infections regress without interventions. Host genetic variations in genes involved in immune response pathways may be related ...
متن کاملGenetic susceptibility to HPV infection and cervical cancer.
Squamous cell carcinoma of the cervix (SCCC) is one of the leading causes of death in developing countries. Infection with high-risk human papillomavirus (HPV) is the major risk factor to develop malignant lesions in the cervix. Polymorphisms of the MHC and p53 genes seem to influence the outcome of HPV infection and progression to SCCC, although controversial data have been reported. MHC are h...
متن کاملmiR-124 rs531564 polymorphism influences genetic susceptibility to cervical cancer.
Cervical cancer is the fourth most common cancer among women worldwide. It most frequently results from human papillomavirus (HPV) infection; however, recent evidence suggests that there may be underlying genetic factors, specifically in regions encoding microRNAs, dictating susceptibility to cervical cancer. This study investigated the relationship between the miR-124 rs531564 gene polymorphis...
متن کاملCervical cancer
سرویکس یا گردن رحم قسمتی از اندام تولید زنانه است که دهانه آن به داخل واژن باز می شود. بعضی اعمال آن عبارتند از : تولید مواد نرم کننده واژن - تولید موکوس که کمک به حرکت اسپرم می کند- حفظ جنین در رحم در طول بارداری
متن کاملGenetic polymorphism of N142D GSTO2 and susceptibility to breast cancer: a meta-analysis
To establish a comprehensive picture of the relationship between glutathione S-transferase omega 2 (GSTO2; MIM: 612314) gene N142D variant (rs. 156697) and breast cancer risk, the present meta-analysis was carried out. Studies published up to July 2012 with information about GSTO2 polymorphism and breast cancer risk were identified using several electronic databases. We identified 4 eligible st...
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ژورنال
عنوان ژورنال: Journal of Biomedical Research
سال: 2011
ISSN: 1674-8301
DOI: 10.1016/s1674-8301(11)60020-1